Chapter 2 Citations

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Inhibits the formation of AGEs. See Starowicz M, Zieliński H. Inhibition of Advanced Glycation End-Product Formation by High Antioxidant-Leveled Spices Commonly Used in European Cuisine. Antioxidants (Basel). 2019 Apr 15;8(4):100. doi: 10.3390/antiox8040100. PMID: 30991695; PMCID: PMC6523868.

That builds collagen and helps joints. See Takasao N, Tsuji-Naito K, Ishikura S, Tamura A, Akagawa M. Cinnamon extract promotes type I collagen biosynthesis via activation of IGF-I signaling in human dermal fibroblasts. J Agric Food Chem. 2012 Feb 8;60(5):1193-200. doi: 10.1021/jf2043357. Epub 2012 Jan 27. PMID: 22233457.

Polyphenols that prevent neurodegenerative diseases like doggy dementia. See Momtaz S, Hassani S, Khan F, Ziaee M, Abdollahi M. Cinnamon, a promising prospect towards Alzheimer’s disease. Pharmacol Res. 2018 Apr;130:241-258. doi: 10.1016/j.phrs.2017.12.011. Epub 2017 Dec 16. PMID: 29258915.

Inhibits the formation of AGEs. See Starowicz M, Zieliński H. Inhibition of Advanced Glycation End-Product Formation by High Antioxidant-Leveled Spices Commonly Used in European Cuisine. Antioxidants (Basel). 2019 Apr 15;8(4):100. doi: 10.3390/antiox8040100. PMID: 30991695; PMCID: PMC6523868.

Eugenol that inhibits inflammation from cytokines. See Bachiega TF, de Sousa JP, Bastos JK, Sforcin JM. Clove and eugenol in noncytotoxic concentrations exert immunomodulatory/anti-inflammatory action on cytokine production by murine macrophages. J Pharm Pharmacol. 2012 Apr;64(4):610-6. doi: 10.1111/j.2042-7158.2011.01440.x. Epub 2012 Feb 7. PMID: 22420667.

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Myricetin, an antioxidant that slows the growth of breast cancer cells. PREETI SHARMA, SHUBHRA CHATURVEDI, MOHD KHAN, et al. Nanoemulsion Myricetin preparation increases the anticancer efficacy against Triple-negative Breast Cancer cells. Authorea. March 21, 2023.

Flavonoid called apigenin that also suppresses the growth of breast cancer cells. See Perrott KM, Wiley CD, Desprez PY, Campisi J. Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells. Geroscience. 2017 Apr;39(2):161-173. doi: 10.1007/s11357-017-9970-1. Epub 2017 Apr 4. PMID: 28378188; PMCID: PMC5411372.

A particularly rich source of vitamin K, which is essential for bone and blood health. See Hozayen WG, El-Desouky MA, Soliman HA, Ahmed RR, Khaliefa AK. Antiosteoporotic effect of Petroselinum crispum, Ocimum basilicum and Cichorium intybus L. in glucocorticoid-induced osteoporosis in rats. BMC Complement Altern Med. 2016 Jun 2;16:165. doi: 10.1186/s12906-016-1140-y. PMID: 27255519; PMCID: PMC4891838.

Polyacetylene, which reduces the carcinogenic effects of aflatoxins. See Peterson S, Lampe JW, Bammler TK, Gross-Steinmeyer K, Eaton DL. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Food Chem Toxicol. 2006 Sep;44(9):1474-84. doi: 10.1016/j.fct.2006.04.010. Epub 2006 Apr 27. PMID: 16762476.

Helps kill cancer cells. See De A, Beligala DH, Birkholz TM, Geusz ME. Anticancer Properties of Curcumin and Interactions With the Circadian Timing System. Integr Cancer Ther. 2019 Dec 9;18:1534735419889154. doi: 10.1177/1534735419889154. PMCID: PMC6902383.

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Shown to increase gut bacteria diversity—especially the bacterial strain Ruminococcaceae. See Kristina S Petersen, Samantha Anderson, Jeremy R Chen See, Jillian Leister, Penny M Kris-Etherton, Regina Lamendella. Herbs and Spices Modulate Gut Bacterial Composition in Adults at Risk for CVD: Results of a Prespecified Exploratory Analysis from a Randomized, Crossover, Controlled-Feeding Study. The Journal of Nutrition, 2022; 152 (11): 2461 DOI: 10.1093/jn/nxac201

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Sulforaphanes in sprouts—especially broccoli sprouts—are highly effective at removing the heavy metals and mycotoxins that are found in abundance in processed dog food. See Elbarbry, Fawzy & Elrody, Nehad. (2011). Potential health benefits of sulforaphane: A review of the experimental, clinical and epidemiological evidences and underlying mechanisms. Journal of medicinal plant research. 5. 473-484.

122 times higher in a dog’s daily diet, compared to average human AGE intake. See van Rooijen C, Bosch G, van der Poel AF, Wierenga PA, Alexander L, Hendriks WH. Quantitation of Maillard reaction products in commercially available pet foods. J Agric Food Chem 2014;62:8883-91. doi: 10.1021/jf502064h.

The sulforaphanes in sprouts activate enzymes that shield the cells from AGEs. Maeda S, Matsui T, Ojima A, Takeuchi M, Yamagishi S. Sulforaphane inhibits advanced glycation end product-induced pericyte damage by reducing expression of receptor for advanced glycation end products. Nutr Res. 2014 Sep;34(9):807-13. doi: 10.1016/j.nutres.2014.08.010. Epub 2014 Aug 29. PMID: 25241332.

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Sanitizing seeds with apple cider vinegar prior to sprouting has been shown to significantly reduce fungal growth. See Escamilla D, Rosso ML, Zhang B. Identification of fungi associated with soybeans and effective seed disinfection treatments. Food Sci Nutr. 2019 Aug 22;7(10):3194-3205. doi: 10.1002/fsn3.1166. PMID: 31660133; PMCID: PMC6804755.

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How to Grow Sprouts. See Evans, Doug. The Sprout Book. 2020 St. Martin’s Publishing Group, NY NY

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